If you want some of the command line parameters to be always used, you can create a file named commandline.ini using an editor and put one command line option per line into the file.
Under Windows save the file in the ZOC program directory (same folder where ZOC.EXE resides).
Under macOS create a file named .zoc8_commandline in your home folder (i.e. /Users/You/.zoc8_commandline).
If you want to work with multiple different sets of command line options (e.g. to make connections from the command line) you can create files with the extension .zsh or .zln and fill them with one command line option per line.
This file extension is automatically associated with ZOC; a double click on such a file will launch ZOC with the file and will thus make it start using the options which are contained within it.
Note: Under macOS using the .zsh extension may be in conflict with other applications, so using .zln is preferable there.